Autophagy and leucine promote chronological longevity and respiration proficiency during calorie restriction in yeast

We have previously shown that autophagy is required for chronological longevity in the budding yeast Saccharomyces cerevisiae. Here we examine the requirements for autophagy during extension of chronological life span (CLS) by calorie restriction (CR). We find that autophagy is upregulated by two CR...

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Autors principals: Aris, John P., Alvers, Ashley L., Ferraiuolo, Roy A., Fishwick, Laura K., Hanvivatpong, Amanda, Hu, Doreen, Kirlew, Christine, Leonard, Michael T., Losin, Kyle J., Marraffini, Michelle, Seo, Arnold Y., Swanberg, Veronica, Westcott, Jennifer L., Wood, Michael S., Leeuwenburgh, Christiaan, Dunn, William A.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728276/
https://ncbi.nlm.nih.gov/pubmed/23337777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2013.01.006
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