Autophagy and leucine promote chronological longevity and respiration proficiency during calorie restriction in yeast

We have previously shown that autophagy is required for chronological longevity in the budding yeast Saccharomyces cerevisiae. Here we examine the requirements for autophagy during extension of chronological life span (CLS) by calorie restriction (CR). We find that autophagy is upregulated by two CR...

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Главные авторы: Aris, John P., Alvers, Ashley L., Ferraiuolo, Roy A., Fishwick, Laura K., Hanvivatpong, Amanda, Hu, Doreen, Kirlew, Christine, Leonard, Michael T., Losin, Kyle J., Marraffini, Michelle, Seo, Arnold Y., Swanberg, Veronica, Westcott, Jennifer L., Wood, Michael S., Leeuwenburgh, Christiaan, Dunn, William A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728276/
https://ncbi.nlm.nih.gov/pubmed/23337777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2013.01.006
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