Macromitophagy is a longevity assurance process that in chronologically aging yeast limited in calorie supply sustains functional mitochondria and maintains cellular lipid homeostasis

Macromitophagy controls mitochondrial quality and quantity. It involves the sequestration of dysfunctional or excessive mitochondria within double-membrane autophagosomes, which then fuse with the vacuole/lysosome to deliver these mitochondria for degradation. To investigate a physiological role of...

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Main Authors: Richard, Vincent R., Leonov, Anna, Beach, Adam, Burstein, Michelle T., Koupaki, Olivia, Gomez-Perez, Alejandra, Levy, Sean, Pluska, Lukas, Mattie, Sevan, Rafeh, Rami, Iouk, Tatiana, Sheibani, Sara, Greenwood, Michael, Vali, Hojatollah, Titorenko, Vladimir I.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2013
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651518/
https://ncbi.nlm.nih.gov/pubmed/23553280
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