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Spatiotemporal mathematical modelling of mutations of the dhps gene in African Plasmodium falciparum

BACKGROUND: Plasmodium falciparum has repeatedly evolved resistance to first-line anti-malarial drugs, thwarting efforts to control and eliminate the disease and in some period of time this contributed largely to an increase in mortality. Here a mathematical model was developed to map the spatiotemp...

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Main Authors: Flegg, Jennifer A, Patil, Anand P, Venkatesan, Meera, Roper, Cally, Naidoo, Inbarani, Hay, Simon I, Sibley, Carol Hopkins, Guerin, Philippe J
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728261/
https://ncbi.nlm.nih.gov/pubmed/23866695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-12-249
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