Determinants for Simultaneous Binding of Copper and Platinum to Human Chaperone Atox1: Hitchhiking not Hijacking

Cisplatin (CisPt) is an anticancer agent that has been used for decades to treat a variety of cancers. CisPt treatment causes many side effects due to interactions with proteins that detoxify the drug before reaching the DNA. One key player in CisPt resistance is the cellular copper-transport system...

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Detaylı Bibliyografya
Asıl Yazarlar: Palm-Espling, Maria E., Andersson, C. David, Björn, Erik, Linusson, Anna, Wittung-Stafshede, Pernilla
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728025/
https://ncbi.nlm.nih.gov/pubmed/23936210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070473
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