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DNA methylation of the glucagon-like peptide 1 receptor (GLP1R) in human pancreatic islets
BACKGROUND: Insulin secretion is enhanced upon the binding of Glucagon-like peptide-1 (GLP-1) to its receptor (GLP1R) in pancreatic β cells. Although a reduced expression of GLP1R in pancreatic islets from type 2 diabetic patients and hyperglycaemic rats has been established, it is still unknown if...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3727960/ https://ncbi.nlm.nih.gov/pubmed/23879380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-14-76 |
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