Association Between BRCA1 and BRCA2 Mutations and Survival in Women with Invasive Epithelial Ovarian Cancer

CONTEXT: Approximately 10 percent of women with invasive epithelial ovarian cancer (EOC) carry deleterious germline mutations in BRCA1 or BRCA2. A recent report suggested that BRCA2 related EOC was associated with an improved prognosis, but the effect of BRCA1 remains unclear. OBJECTIVE: To characte...

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গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Bolton, Kelly L., Chenevix-Trench, Georgia, Goh, Cindy, Sadetzki, Siegal, Ramus, Susan J., Karlan, Beth Y., Lambrechts, Diether, Despierre, Evelyn, Barrowdale, Daniel, McGuffog, Lesley, Healey, Sue, Easton, Douglas F., Sinilnikova, Olga, Benitez, Javier, García, María J., Neuhausen, Susan, Gail, Mitchell H., Hartge, Patricia, Peock, Susan, Frost, Debra, Evans, D. Gareth, Eeles, Ros, Godwin, Andrew K., Daly, Mary B., Kwong, Ava, Ma, Edmond SK, Lázaro, Conxi, Blanco, Ignacio, Montagna, Marco, D’Andrea, Emma, Nicoletto, Ornella, Investigators, kConFab, Johnatty, Sharon E., Kjær, Susanne Krüger, Jensen, Allan, Høgdall, Estrid, Goode, Ellen L., Fridley, Brooke L., Loud, Jennifer T., Greene, Mark H., Mai, Phuong L., Chetrit, Angela, Lubin, Flora, Hirsh-Yechezkel, Galit, Glendon, Gord, Andrulis, Irene L., Toland, Amanda E., Senter, Leigha, Gore, Martin E., Gourley, Charlie, Michie, Caroline O, Song, Honglin, Tyrer, Jonathan, Whittemore, Alice S., McGuire, Valerie, Sieh, Weiva, Kristoffersson, Ulf, Olsson, Håkan, Borg, Åke, Levine, Douglas A., Steele, Linda, Beattie, Mary S., Chan, Salina, Nussbaum, Robert, Moysich, Kirsten B., Gross, Jenny, Cass, Ilana, Walsh, Christine, Li, Andrew J., Leuchter, Ronald, Gordon, Ora, Garcia-Closas, Montserrat, Gayther, Simon A., Chanock, Stephen J., Antoniou, Antonis C., Pharoah, Paul D.P.
বিন্যাস: Artigo
ভাষা:Inglês
প্রকাশিত: 2012
বিষয়গুলি:
Article
অনলাইন ব্যবহার করুন:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727895/
https://ncbi.nlm.nih.gov/pubmed/22274685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2012.20
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