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Therapeutic inhibition of cathepsin K—reducing bone resorption while maintaining bone formation

Osteoporosis is a disease of high bone remodeling with an imbalance of bone resorption over bone formation, resulting in decreased bone mineral density and deterioration of bone microarchitecture. From the emerging understandings of the molecular and cellular regulators of bone remodeling, potential...

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Autor principal: Duong, Le T
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727753/
https://ncbi.nlm.nih.gov/pubmed/23951460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bonekey.2012.67
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