Analysing the visible conformational substates of the FK506-binding protein FKBP12

The (1)H-(15)N 2D NMR correlation spectrum of the widely studied FK506-binding protein FKBP12 (FK506-binding protein of 12 kDa) contains previously unreported peak doublings for at least 31 residues that arise from a minor conformational state (12% of total) which exchanges with the major conformati...

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Bibliographic Details
Main Authors: Mustafi, Sourajit M., Chen, Hui, Li, Hongmin, LeMaster, David M., Hernández, Griselda
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727217/
https://ncbi.nlm.nih.gov/pubmed/23688288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20130276
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