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Microglia Are Essential to Masculinization of Brain and Behavior
Brain sexual differentiation in rodents results from the perinatal testicular androgen surge. In the preoptic area (POA), estradiol aromatized from testosterone upregulates the production of the proinflammatory molecule, prostaglandin E(2) (PGE(2)) to produce sex-specific brain development. PGE(2) p...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3727162/ https://ncbi.nlm.nih.gov/pubmed/23407936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1268-12.2013 |
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