Microglia Are Essential to Masculinization of Brain and Behavior

Brain sexual differentiation in rodents results from the perinatal testicular androgen surge. In the preoptic area (POA), estradiol aromatized from testosterone upregulates the production of the proinflammatory molecule, prostaglandin E(2) (PGE(2)) to produce sex-specific brain development. PGE(2) p...

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Bibliografiske detaljer
Main Authors: Lenz, Kathryn M., Nugent, Bridget M., Haliyur, Rachana, McCarthy, Margaret M.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2013
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727162/
https://ncbi.nlm.nih.gov/pubmed/23407936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1268-12.2013
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