Adenylyl cyclase type 5 in cardiac disease, metabolism, and aging

G protein-coupled receptor/adenylyl cyclase (AC)/cAMP signaling is crucial for all cellular responses to physiological and pathophysiological stimuli. There are nine isoforms of membrane-bound AC, with type 5 being one of the two major isoforms in the heart. Since the role of AC in the heart in regu...

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Autors principals: Vatner, Stephen F., Park, Misun, Yan, Lin, Lee, Grace J., Lai, Lo, Iwatsubo, Kousaku, Ishikawa, Yoshihiro, Pessin, Jeffrey, Vatner, Dorothy E.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2013
Matèries:
Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727099/
https://ncbi.nlm.nih.gov/pubmed/23624627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00080.2013
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