Prevention of heart failure in mice by an antiviral agent that inhibits type 5 cardiac adenylyl cyclase

Despite numerous discoveries from genetically engineered mice, relatively few have been translated to the bedside, mainly because it is difficult to translate from genes to drugs. This investigation examines an antiviral drug, which also has an action to selectively inhibit type 5 adenylyl cyclase (...

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Detalhes bibliográficos
Main Authors: Iwatsubo, Kosaku, Bravo, Claudio, Uechi, Masami, Baljinnyam, Erdene, Nakamura, Takashi, Umemura, Masanari, Lai, Lo, Gao, Shumin, Yan, Lin, Zhao, Xin, Park, Misun, Qiu, Hongyu, Okumura, Satoshi, Iwatsubo, Mizuka, Vatner, Dorothy E., Vatner, Stephen F., Ishikawa, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Integrative Cardiovascular Physiology and Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378263/
https://ncbi.nlm.nih.gov/pubmed/22505646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00190.2012
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