Prevention of heart failure in mice by an antiviral agent that inhibits type 5 cardiac adenylyl cyclase

Despite numerous discoveries from genetically engineered mice, relatively few have been translated to the bedside, mainly because it is difficult to translate from genes to drugs. This investigation examines an antiviral drug, which also has an action to selectively inhibit type 5 adenylyl cyclase (...

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Main Authors: Iwatsubo, Kosaku, Bravo, Claudio, Uechi, Masami, Baljinnyam, Erdene, Nakamura, Takashi, Umemura, Masanari, Lai, Lo, Gao, Shumin, Yan, Lin, Zhao, Xin, Park, Misun, Qiu, Hongyu, Okumura, Satoshi, Iwatsubo, Mizuka, Vatner, Dorothy E., Vatner, Stephen F., Ishikawa, Yoshihiro
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2012
Teme:
Integrative Cardiovascular Physiology and Pathophysiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378263/
https://ncbi.nlm.nih.gov/pubmed/22505646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00190.2012
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