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Compartment Model Predicts VEGF Secretion and Investigates the Effects of VEGF Trap in Tumor-Bearing Mice

Angiogenesis, the formation of new blood vessels from existing vasculature, is important in tumor growth and metastasis. A key regulator of angiogenesis is vascular endothelial growth factor (VEGF), which has been targeted in numerous anti-angiogenic therapies aimed at inhibiting tumor angiogenesis....

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Autors principals: Finley, Stacey D., Dhar, Manjima, Popel, Aleksander S.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727077/
https://ncbi.nlm.nih.gov/pubmed/23908970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2013.00196
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