Targeting the brain with PEG-PLGA nanoparticles modified with phage-displayed peptides

The relative impermeability of the blood-brain barrier (BBB) results from tight junctions and efflux transport systems limits drug delivery to the central nervous system (CNS), and thus severely restricts the therapy of many central nervous system diseases. In order to enhance the brain-specific dru...

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Detalhes bibliográficos
Main Authors: Li, Jingwei, Feng, Liang, Fan, Li, Zha, Yuan, Guo, Liangran, Zhang, Qizhi, Chen, Jun, Pang, Zhiqing, Wang, Yuchen, Jiang, Xinguo, Yang, Victor C., Wen, Longping
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727047/
https://ncbi.nlm.nih.gov/pubmed/21470674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2011.03.031
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