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Modeling serotonin uptake in the lung shows endothelial transporters dominate over cleft permeation

A four-region (capillary plasma, endothelium, interstitial fluid, cell) multipath model was configured to describe the kinetics of blood-tissue exchange for small solutes in the lung, accounting for regional flow heterogeneity, permeation of cell membranes and through interendothelial clefts, and in...

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Bibliographic Details
Main Authors: Jardine, Bartholomew, Bassingthwaighte, James B.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726944/
https://ncbi.nlm.nih.gov/pubmed/23645496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00420.2012
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