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Structural Analysis of the Extracellular Entrance to the Serotonin Transporter Permeation Pathway

Neurotransmitter transporters are responsible for removal of biogenic amine neurotransmitters after release into the synapse. These transporters are the targets for many clinically relevant drugs, such as antidepressants and psychostimulants. A high resolution crystal structure for the monoamine tra...

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Detalhes bibliográficos
Main Authors: Torres-Altoro, Melissa I., Kuntz, Charles P., Nichols, David E., Barker, Eric L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865310/
https://ncbi.nlm.nih.gov/pubmed/20304925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.088138
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