Correction of Cobalamin Malabsorption in Pancreatic Insufficiency with a Cobalamin Analogue that Binds with High Affinity to R Protein but not to Intrinsic Factor

In vitro studies indicate that [(57)Co]cobalamin (Cbl) is preferentially bound to salivary R protein as opposed to intrinsic factor (IF) and that [(57)Co]Cbl bound to R protein is not transferred to IF at either pH 2 or pH 8. Incubation of R protein-[(57)Co]Cbl with pancreatic proteases causes a par...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	J Clin Invest
Autori principali:	Allen, Robert H., Seetharam, Bellur, Allen, Nancy C., Podell, Elaine R., Alpers, David H.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1978
Soggetti:	Articles
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372689/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/659618/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109083
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!