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Differential Programming of B Cells in AID Deficient Mice
The Aicda locus encodes the activation induced cytidine deaminase (AID) and is highly expressed in germinal center (GC) B cells to initiate somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin (Ig) genes. Besides these Ig specific activities in B cells, AID has been imp...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3726761/ https://ncbi.nlm.nih.gov/pubmed/23922811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069815 |
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