Dosage-dependent tumor suppression by histone deacetylases 1 and 2 through regulation of c-Myc collaborating genes and p53 function

Histone deacetylases (HDACs) are epigenetic erasers of lysine-acetyl marks. Inhibition of HDACs using small molecule inhibitors (HDACi) is a potential strategy in the treatment of various diseases and is approved for treating hematological malignancies. Harnessing the therapeutic potential of HDACi...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Heideman, Marinus R., Wilting, Roel H., Yanover, Eva, Velds, Arno, de Jong, Johann, Kerkhoven, Ron M., Jacobs, Heinz, Wessels, Lodewyk F., Dannenberg, Jan-Hermen
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2013
Schlagworte:
Lymphoid Neoplasia
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596963/
https://ncbi.nlm.nih.gov/pubmed/23327920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-08-450916
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge