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Ron Knockdown and Ron Monoclonal Antibody IMC-RON8 Sensitize Pancreatic Cancer to Histone Deacetylase Inhibitors (HDACi)

Recepteur d’origine nantais (Ron) is overexpressed in a panel of pancreatic cancer cells and tissue samples from pancreatic cancer patients. Ron can be activated by its ligand macrophage stimulating protein (MSP), thereby activating oncogenic signaling pathways. Crosstalk between Ron and EGFR, c-Met...

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Detalhes bibliográficos
Main Authors: Zou, Yi, Howell, Gillian M., Humphrey, Lisa E., Wang, Jing, Brattain, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726703/
https://ncbi.nlm.nih.gov/pubmed/23922886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069992
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