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Epitope Mapping of Conformational V2-specific Anti-HIV Human Monoclonal Antibodies Reveals an Immunodominant Site in V2

In the case-control study of the RV144 vaccine trial, the levels of antibodies to the V1V2 region of the gp120 envelope glycoprotein were found to correlate inversely with risk of HIV infection. This recent demonstration of the potential role of V1V2 as a vaccine target has catapulted this region in...

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Detalhes bibliográficos
Main Authors: Mayr, Luzia M., Cohen, Sandra, Spurrier, Brett, Kong, Xiang-Peng, Zolla-Pazner, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726596/
https://ncbi.nlm.nih.gov/pubmed/23923028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070859
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