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Interacting Effects of Sulfonylureas and Glucose on Cyclic AMP Metabolism and Insulin Release in Pancreatic Islets of the Rat

The effects of tolbutamide and glibenclamide on the metabolism of cyclic AMP were investigated in pancreatic islets of the rat. Changes in cyclic AMP were assessed by measuring [(3)H]cyclic AMP after labeling of the islets with [2-(3)H]adenine. In the presence of a nonstimulatory concentration of gl...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Principais autores: Grill, V., Cerasi, E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 1978
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372657/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/207736/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109052
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