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Measuring Mitochondrial Metabolism in Rat Brain in vivo using MR Spectroscopy of Hyperpolarized [2-(13)C]Pyruvate
Hyperpolarized [1-(13)C]pyruvate (Pyr) has been used to assess metabolism in healthy and diseased states, focusing on downstream labeling of lactate (Lac), bicarbonate (Bic), and alanine. Whereas hyperpolarized [2-(13)C]Pyr, which retains the labeled carbon when Pyr is converted to acetyl-coenzyme A...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3726546/ https://ncbi.nlm.nih.gov/pubmed/23553852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.2935 |
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