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Characterisation of the gene encoding type II DNA topoisomerase from Leishmania donovani: a key molecular target in antileishmanial therapy

The gene encoding type II DNA topoisomerase from the kinetoplastid hemoflagellated protozoan parasite Leishmania donovani (LdTOP2) was isolated from a genomic DNA library of this parasite. DNA sequence analysis revealed an ORF of 3711 bp encoding a putative protein of 1236 amino acids with no intron...

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Main Authors: Das, Aditi, Dasgupta, Arindam, Sharma, Shalini, Ghosh, Monidipa, Sengupta, Tanushri, Bandopadhyay, Santu, Majumder, Hemanta K.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC37264/
https://ncbi.nlm.nih.gov/pubmed/11328867
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