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Functional dissection of the C-terminal domain of type II DNA topoisomerase from the kinetoplastid hemoflagellate Leishmania donovani

The amino acid sequences of the C-terminal domain (CTD) of the type II DNA topoisomerases are divergent and species specific as compared with the highly conserved N-terminal and central domains. A set of C-terminal deletion mutants of Leishmania donovani topoisomerase II was constructed. Removal of...

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Detalhes bibliográficos
Main Authors: Sengupta, Tanushri, Mukherjee, Mandira, Mandal, Chhabinath, Das, Aditi, Majumder, Hemanta K.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC203312/
https://ncbi.nlm.nih.gov/pubmed/12954766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg727
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