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Thrombin generation and secretion of platelet Factor 4 during blood clotting.

We have studied the platelet release reaction and thrombin generation during the spontaneous clotting of whole blood in vitro. Both thrombin formation and secretion of platelet Factor 4 were detected at least 12 min before clotting (clotting time, 22--26 min). Initially, at low thrombin concentratio...

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Библиографические подробности
Опубликовано в::J Clin Invest
Главные авторы: Shuman, M A, Levine, S P
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 1978
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372628/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/207723/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109010
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