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The measurement of thrombin in clotting blood by radioimmunoassay.

We have developed a radioimmunoassay for human thrombin using rabbit anti-human thrombin IgG. The assay can measure 2 ng thrombin/ml plasma, 500-fold more sensitive than clotting assays. Human prothrombin is less reactive in the assay than thrombin by at least four orders of magnitude, and there is...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Shuman, M A, Majerus, P W
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1976
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333294/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/993343/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108579
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