Thrombin generation and secretion of platelet Factor 4 during blood clotting.

We have studied the platelet release reaction and thrombin generation during the spontaneous clotting of whole blood in vitro. Both thrombin formation and secretion of platelet Factor 4 were detected at least 12 min before clotting (clotting time, 22--26 min). Initially, at low thrombin concentratio...

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Pubblicato in:	J Clin Invest
Autori principali:	Shuman, M A, Levine, S P
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1978
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372628/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/207723/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109010
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