125I-insulin binding to cultured human lymphocytes. Initial localization and fate of hormone determined by quantitative electron microscopic autoradiography.

Morphologic and biochemical studies indicate that the initial action of insulin is binding to a cell surface receptor. Whether further translocation of the hormone, or a product of the hormone, occurs is unclear and has not been investigated by direct means. To determine the fate of 125I-insulin bou...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	J Clin Invest
Päätekijät:	Carpentier, J L, Gorden, P, Amherdt, M, Van Obberghen, E, Kahn, C R, Orci, L
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	American Society for Clinical Investigation 1978
Aiheet:	Research Article
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372623/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/659578/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109005
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