125I-insulin binding to cultured human lymphocytes. Initial localization and fate of hormone determined by quantitative electron microscopic autoradiography.

Morphologic and biochemical studies indicate that the initial action of insulin is binding to a cell surface receptor. Whether further translocation of the hormone, or a product of the hormone, occurs is unclear and has not been investigated by direct means. To determine the fate of 125I-insulin bou...

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Main Authors: Carpentier, J L, Gorden, P, Amherdt, M, Van Obberghen, E, Kahn, C R, Orci, L
Format: Artigo
Jezik:Inglês
Izdano: 1978
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC372623/
https://ncbi.nlm.nih.gov/pubmed/659578
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