Survivin Is a Therapeutic Target in Merkel Cell Carcinoma

Merkel cell polyomavirus (MCV) causes ~80% of primary and metastatic Merkel cell carcinomas (MCCs). By comparing digital transcriptome subtraction deep-sequencing profiles, we found that transcripts of the cellular survivin oncoprotein [BIRC5a (baculoviral inhibitor of apoptosis repeat-containing 5)...

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Autori principali: Arora, Reety, Shuda, Masahiro, Guastafierro, Anna, Feng, Huichen, Toptan, Tuna, Tolstov, Yanis, Normolle, Daniel, Vollmer, Laura L., Vogt, Andreas, Dömling, Alexander, Brodsky, Jeffrey L., Chang, Yuan, Moore, Patrick S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726222/
https://ncbi.nlm.nih.gov/pubmed/22572880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3003713
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