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Merkel cell polyomavirus T antigens promote cell proliferation and inflammatory cytokine gene expression
Merkel cell polyomavirus (MCV) is clonally integrated in over 80 % of Merkel cell carcinomas and mediates tumour development through the expression of viral oncoproteins, the large T (LT) and small T antigens (sT). Viral integration is associated with signature mutations in the T-antigen locus that...
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| Published in: | J Gen Virol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Microbiology Society
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4804762/ https://ncbi.nlm.nih.gov/pubmed/26385761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000287 |
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