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Mechanism of Alkoxy Groups Substitution by Grignard Reagents on Aromatic Rings and Experimental Verification of Theoretical Predictions of Anomalous Reactions

The mechanism of direct displacement of alkoxy groups in vinylogous and aromatic esters by Grignard reagents, a reaction that is not observed with expectedly better tosyloxy leaving groups, is elucidated computationally. The mechanism of this reaction has been determined to proceed through the inner...

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Detalhes bibliográficos
Main Authors: Jiménez-Osés, Gonzalo, Brockway, Anthony J., Shaw, Jared T., Houk, K. N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726219/
https://ncbi.nlm.nih.gov/pubmed/23601086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4015937
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