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Somitic disruption of GNAS in chick embryos mimics progressive osseous heteroplasia
Progressive osseous heteroplasia (POH) is a rare developmental disorder of heterotopic ossification (HO) caused by heterozygous inactivating germline mutations in the paternal allele of the GNAS gene. Interestingly, POH lesions have a bewildering mosaic distribution. Using clinical, radiographic, an...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3726175/ https://ncbi.nlm.nih.gov/pubmed/23863715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69746 |
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