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Pharmacokinetic-Pharmacodynamic Disease Progression Model for Effect of Etanercept in Lewis Rats with Collagen-Induced Arthritis
PURPOSE: To develop a pharmacokinetic-pharmacodynamic disease progression (PK/PD/DIS) model to characterize the effect of etanercept in collagen-induced arthritis (CIA) rats on rheumatoid arthritis (RA) progression. METHODS: The CIA rats received either 5 mg/kg intravenous (IV), 1 mg/kg IV, or 5 mg/...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3726066/ https://ncbi.nlm.nih.gov/pubmed/21360252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-011-0396-7 |
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