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Quinlobelane: A water-soluble lobelane analogue and inhibitor of VMAT2
Replacing the phenyl groups in the structure of the VMAT2 inhibitor, lobelane with either pyridyl, quinolyl or indolyl groups affords novel analogues with improved water solubility. The synthetic methodologies reported herein also underscore the paucity of hydrogenation methods that offer selectivit...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3726001/ https://ncbi.nlm.nih.gov/pubmed/20494575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.04.117 |
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