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Activation of muscarinic M(3) receptors inhibits large-conductance voltage- and Ca(2+)-activated K(+) channels in rat urinary bladder smooth muscle cells

Large conductance voltage- and Ca(2+)-activated K(+) (BK) channels are key regulators of detrusor smooth muscle (DSM) contraction and relaxation during urine voiding and storage. Here, we explored whether BK channels are regulated by muscarinic receptors (M-Rs) in native freshly isolated rat DSM cel...

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Autori principali: Parajuli, Shankar P., Petkov, Georgi V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725628/
https://ncbi.nlm.nih.gov/pubmed/23703523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00113.2013
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