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The Phosphatase PP4c Controls Spindle Orientation to Maintain Proliferative Symmetric Divisions in the Developing Neocortex

In the developing neocortex, progenitor cells expand through symmetric division before they generate cortical neurons through multiple rounds of asymmetric cell division. Here, we show that the orientation of the mitotic spindle plays a crucial role in regulating the transition between those two div...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Xie, Yunli, Jüschke, Christoph, Esk, Christopher, Hirotsune, Shinji, Knoblich, Juergen A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cell Press 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725415/
https://ncbi.nlm.nih.gov/pubmed/23830831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.05.027
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