The Phosphatase PP4c Controls Spindle Orientation to Maintain Proliferative Symmetric Divisions in the Developing Neocortex

In the developing neocortex, progenitor cells expand through symmetric division before they generate cortical neurons through multiple rounds of asymmetric cell division. Here, we show that the orientation of the mitotic spindle plays a crucial role in regulating the transition between those two div...

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Detaylı Bibliyografya
Asıl Yazarlar: Xie, Yunli, Jüschke, Christoph, Esk, Christopher, Hirotsune, Shinji, Knoblich, Juergen A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cell Press 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725415/
https://ncbi.nlm.nih.gov/pubmed/23830831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.05.027
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