Stimulation of Proglucagon Gene Expression by Human GPR119 in Enteroendocrine L-cell Line GLUTag

GPR119 is a G protein-coupled receptor expressed on enteroendocrine L-cells that synthesize and secrete the incretin hormone glucagon-like peptide-1 (GLP-1). Although GPR119 agonists stimulate L-cell GLP-1 secretion, there is uncertainty concerning whether GLP-1 biosynthesis is under the control of...

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Autori principali: Chepurny, Oleg G., Bertinetti, Daniela, Diskar, Mandy, Leech, Colin A., Afshari, Parisa, Tsalkova, Tamara, Cheng, Xiaodong, Schwede, Frank, Genieser, Hans-G., Herberg, Friedrich W., Holz, George G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2013
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725342/
https://ncbi.nlm.nih.gov/pubmed/23798572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2013-1029
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