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Combinatorial triple-selective labeling as a tool to assist membrane protein backbone resonance assignment

Obtaining NMR assignments for slowly tumbling molecules such as detergent-solubilized membrane proteins is often compromised by low sensitivity as well as spectral overlap. Both problems can be addressed by amino-acid specific isotope labeling in conjunction with (15)N–(1)H correlation experiments....

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Löhr, Frank, Reckel, Sina, Karbyshev, Mikhail, Connolly, Peter J., Abdul-Manan, Norzehan, Bernhard, Frank, Moore, Jonathan M., Dötsch, Volker
التنسيق: Artigo
اللغة:Inglês
منشور في: 2012
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725308/
https://ncbi.nlm.nih.gov/pubmed/22252484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-012-9601-1
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