From nanodiscs to isotropic bicelles: a procedure for solution NMR studies of detergent sensitive integral membrane proteins

Nanodiscs and isotropic bicelles are promising membrane mimetics in the field of solution NMR spectroscopy of integral membrane proteins (IMPs). Despite varied challenges to solution NMR studies of IMPs, we attribute the paucity of solution NMR structures in these environments to the inability of di...

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Detalhes bibliográficos
Publicado no:Structure
Main Authors: Laguerre, Aisha, Löhr, Frank, Henrich, Erik, Hoffmann, Beate, Abdul-Manan, Norzehan, Connolly, Peter J., Perozo, Eduardo, Moore, Jonathan M., Bernhard, Frank, Dötsch, Volker
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5064851/
https://ncbi.nlm.nih.gov/pubmed/27618661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2016.07.017
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