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Kinesin-12 differentially affects spindle assembly depending on its microtubule substrate
BACKGROUND: During mitosis, the microtubule (MT) cytoskeleton rearranges into a bipolar spindle that drives chromosome segregation. Two kinesin subtypes, kinesin-5 and kinesin-12, help build this bipolar array by separating the spindle poles. However, unlike kinesin-5, the kinesin-12 mechanism is no...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3725213/ https://ncbi.nlm.nih.gov/pubmed/23791727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2013.05.043 |
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