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Kinesin-5 inhibitor resistance is driven by kinesin-12
The microtubule (MT) cytoskeleton bipolarizes at the onset of mitosis to form the spindle. In animal cells, the kinesin-5 Eg5 primarily drives this reorganization by actively sliding MTs apart. Its primacy during spindle assembly renders Eg5 essential for mitotic progression, demonstrated by the let...
Guardat en:
| Publicat a: | J Cell Biol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5084272/ https://ncbi.nlm.nih.gov/pubmed/27091450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201507036 |
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