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Kinesin-5 inhibitor resistance is driven by kinesin-12
The microtubule (MT) cytoskeleton bipolarizes at the onset of mitosis to form the spindle. In animal cells, the kinesin-5 Eg5 primarily drives this reorganization by actively sliding MTs apart. Its primacy during spindle assembly renders Eg5 essential for mitotic progression, demonstrated by the let...
Uloženo v:
| Vydáno v: | J Cell Biol |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Rockefeller University Press
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5084272/ https://ncbi.nlm.nih.gov/pubmed/27091450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201507036 |
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