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Quantitation of Benzo[a]pyrene Metabolic Profiles in Human Bronchoalveolar H358) Cells by Stable Isotope Dilution Liquid Chromatography-Atmospheric Chemical Ionization Mass Spectrometry

Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental pollutants and are carcinogenic in multiple organs and species. Benzo[a]pyrene (B[a]P) is a representative PAH and has been studied extensively for its carcinogenicity and toxicity. B[a]P itself is chemically inert and requires met...

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Bibliographic Details
Main Authors: Lu, Ding, Harvey, Ronald G., Blair, Ian A., Penning, Trevor M.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725129/
https://ncbi.nlm.nih.gov/pubmed/21962213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx2002614
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