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tRNA tK(UUU), tQ(UUG), and tE(UUC) wobble position modifications fine-tune protein translation by promoting ribosome A-site binding
tRNA modifications are crucial to ensure translation efficiency and fidelity. In eukaryotes, the URM1 and ELP pathways increase cellular resistance to various stress conditions, such as nutrient starvation and oxidative agents, by promoting thiolation and methoxycarbonylmethylation, respectively, of...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3725067/ https://ncbi.nlm.nih.gov/pubmed/23836657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1300781110 |
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