tRNA tK(UUU), tQ(UUG), and tE(UUC) wobble position modifications fine-tune protein translation by promoting ribosome A-site binding

tRNA modifications are crucial to ensure translation efficiency and fidelity. In eukaryotes, the URM1 and ELP pathways increase cellular resistance to various stress conditions, such as nutrient starvation and oxidative agents, by promoting thiolation and methoxycarbonylmethylation, respectively, of...

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Bibliographic Details
Main Authors: Rezgui, Vanessa Anissa Nathalie, Tyagi, Kshitiz, Ranjan, Namit, Konevega, Andrey L., Mittelstaet, Joerg, Rodnina, Marina V., Peter, Matthias, Pedrioli, Patrick G. A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2013
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725067/
https://ncbi.nlm.nih.gov/pubmed/23836657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1300781110
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