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Thermodynamic framework for identifying free energy inventories of enzyme catalytic cycles
Pauling’s suggestion that enzymes are complementary in structure to the activated complexes of the reactions they catalyze has provided the conceptual basis to explain how enzymes obtain their fantastic catalytic prowess, and has served as a guiding principle in drug design for over 50 y. However, t...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3725039/ https://ncbi.nlm.nih.gov/pubmed/23840058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310964110 |
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