The number of catalytic cycles in an enzyme’s lifetime and why it matters to metabolic engineering

Metabolic engineering uses enzymes as parts to build biosystems for specified tasks. Although a part’s working life and failure modes are key engineering performance indicators, this is not yet so in metabolic engineering because it is not known how long enzymes remain functional in vivo or whether...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Hanson, Andrew D., McCarty, Donald R., Henry, Christopher S., Xian, Xiaochen, Joshi, Jaya, Patterson, Jenelle A., García-García, Jorge D., Fleischmann, Scott D., Tivendale, Nathan D., Millar, A. Harvey
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020674/
https://ncbi.nlm.nih.gov/pubmed/33753504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2023348118
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