The number of catalytic cycles in an enzyme’s lifetime and why it matters to metabolic engineering

Metabolic engineering uses enzymes as parts to build biosystems for specified tasks. Although a part’s working life and failure modes are key engineering performance indicators, this is not yet so in metabolic engineering because it is not known how long enzymes remain functional in vivo or whether...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Hanson, Andrew D., McCarty, Donald R., Henry, Christopher S., Xian, Xiaochen, Joshi, Jaya, Patterson, Jenelle A., García-García, Jorge D., Fleischmann, Scott D., Tivendale, Nathan D., Millar, A. Harvey
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2021
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020674/
https://ncbi.nlm.nih.gov/pubmed/33753504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2023348118
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